Team 2: Ion channels remodeling, PH predisposing genes, and technological innovation
Fabrice Antigny & David Montani
Embedded Files
Research topics
Research topics
The global goal of Team 2 of UMR_S 999 is to understand the pathophysiological mechanisms of pulmonary hypertension (PH) at cellular and organ levels (i.e., the lung and heart) in order to develop effective treatment strategies. Our research focuses on:
(1) to explore the cellular mechanisms and molecular aspects of PH, including ion channel remodeling, PH-predisposing genes, transcription factors, and RNA-binding proteins.
(2) to decipher the mechanism of right ventricular remodeling and dysfunction occurring in PH
(3) to develop a long-term ex vivo human heart and lung perfusion platform, and enhance the reliability of a temporary artificial lung
Team 2 comprises researchers, physicians, surgeons, post-docs, engineers, and PhD students who are working together to develop translational research from the bench to the bedside for the benefit of patients with PH.
Team members
Principal Investigators / Senior Researchers
-ANTIGNY Fabrice; PhD [ORCID ID]
-BAUER Fabrice; MD, PhD [ORCID ID]
-BOËT Angèle; MD, PhD [ORCID ID]
-CAPUANO Véronique; PhD [ORCID ID]
-COHEN-KAMINSKY Sylvia, PhD [ORCID ID]
-FADEL Elie; MD, PhD [ORCID ID]
-GUIHAIRE Julien; MD, PhD [ORCID ID]
-HASCOËT Sébastien; MD, PhD [ORCID ID]
-HAULON Stephan ; MD, PhD [ORCID ID]
-LE PAVEC Jérôme; MD, PhD [ORCID ID]
-MERCIER Olaf; MD, PhD [ORCID ID]
-MONTANI David; MD, PhD [ORCID ID]
-RUFFENACH Grégoire; PhD [ORCID ID]
-STEPHAN François; MD, PhD
Post-Doc
-MERCIER Julia; PhD [ORCID ID]
-NABORY Yuya; MD, PhD
-LE RIBEUZ Hélène; PhD [ORCID ID]
-SAINT-MARTIN WILLER Anaïs; PhD [ORCID ID]
PhD Students
-ABGRAL Maëlig; MD
-AGUADO Benoît; MD [ORCID ID]
-AKAMKAM Ali; MD [ORCID ID]
-AZARINE Arshid; MD [ORCID ID]
-BEURNIER Antoine; MD [ORCID ID]
-CIOBOTARU Vlad; MD [ORCID ID]
-DANG VAN Simon; MD [ORCID ID]
-DUMONT Florent; [ORCID ID]
-EL JEKMEK Kristelle; [ORCID ID]
-FOURNIER Emmanuelle; MD [ORCID ID]
-GENECAND Léon; MD [ORCID ID]
-HADDAD Raymond; MD [ORCID ID]
-ISSARD Justin; MD [ORCID ID]
-LACOSTE-PALASSET Thomas; MD [ORCID ID]
-PRADERE Pauline; MD [ORCID ID]
-TROUILLE Maël;
-VALDEOLMILLOS PADRINO Estibaliz; MD [ORCID ID]
Engineers & Technical Staff
-DECANTE Benoït (Engineer)
-DUTHEIL Mary (Engineer)
-GOULARD Jennifer (Administrator)
-GOURMELON Mathieu (Engineer) [ORCID ID]
-SCHENIN-KING Claudine (Technician)
Alumni members
Alumni members
Dr. Anaïs Saint-Martin Willer: Master student / PhD student (2022-2025)
Dr. Benoit Aguado, MD: Master student (2025)
Victoire Burnel: Engineer (2025)
Moniroth Singh: Master student (2025)
Rochnel Awannini: Bachelor student (2025)
Dr. Angèle Boët, MD, PhD: PhD student (2018-2024)
Dr. Julien Grynblat, MD, PhD: Master student / PhD student (2020-2024)
Dr. Manon Leveque, MD: Master student (2024)
Léa Baziz: Master student (2024)
Nelly Dey: Master student (2024)
Tracy Bous Chayaa: Master student (2024)
Dr. Gomes Joana, PhD: PhD Student from the University of Porto (2023-2024)
Asheley Dos Santos: Undergraduate Student BTS (2023-2024)
Dr. Bastien Masson, PhD: PhD student (2020-2023)
Dr. Firmin Akoumia, PhD: Master student / PhD Student (2018-2023)
Dr. Lucille Penalva-Mousset, PhD: PhD student (2020-2023)
Margaux Malosse: Bachelor Student (2023)
Juliette Pilloy: Bachelor Student (2023)
Dr. Ali Akamkam, MD: Master student (2023)
Dr. Guillaume Fadel, MD: Master student (2023)
Dr. Antoine Beauvais, MD: Master student (2022)
Dr. Hélène Le Ribeuz, PhD: PhD student (2019-2022)
Dr. Bahgat Soilih, PhD: PhD student (2019-2022)
Dr. Dorothée Brunet, MD: Master student (2022)
Dr. Grégoire Manaud, PhD: PhD student (2018-2021)
Loann Laubry: Master student (2021)
Dr. Thomas Lacoste, MD: Master student (2020)
Raja Chebbi: Master student (2020)
Léa Bernard: Master student (2020)
Dr. Julien Caliez, MD: Master student (2019)
Dr. Marceau Quatredeniers, PhD: PhD student / post-doc (2014-2019)
Dr. Mélanie Lambert, PhD: Master student / PhD student (2016-2019)
Dr. Saïd Amissi, PhD: Post Doc (2016-2019)
Dr. Benoit Ranchoux, PhD: PhD student (2014-2018)
Dr. Marianne Riou, MD: Master student (2018)
Dr. Sébastien Dumas, PhD: PhD student / Post-doc (2013-2018)
Dr. Giles Bru-Mercier, PhD: Post Doc (2011-2018)
Lucie To: Master student (2018)
Dr. Aurélie Hautefort, PhD: PhD student (2014-2017)
Dr. Audrey Courboulin, PhD: Post Doc (2015-2017)
Dr. Nicolas Doisne, PhD: Post Doc (2015-2017)
Dr. Sven Gunther, MD: Master student (2015)
Page updated
Google Sites
Report abuse